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YKL-06-061

CAT: 0804-HY-120056-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-120056-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].
CAS Number
2172617-15-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Salt-inducible Kinase (SIK)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ykl-06-061.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C1N(C2=NC(NC3=CC=C(C=C3OC)N4CCN(CC4)C)=NC=C2CN1C5=C(C=CC=C5C)C)C6CCC6
Molecular Formula
C30H37N7O2
Molecular Weight
527.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19 (11) :2177-2184.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIK1

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