MK-0343 (Standard)
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MK-0343 (Standard)
Description :
MK-0343 (Standard) is the analytical standard of MK-0343. This product is intended for research and analytical applications. MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic[1].Product Name Alternative :
MRK-409 (Standard)UNSPSC :
12352005Target :
GABA Receptor; Reference StandardsRelated Pathways :
Membrane Transporter/Ion Channel; Neuronal Signaling; OthersField of Research :
Neurological DiseaseSmiles :
CN1N=CN=C1COC2=NN3C(C=C2C4CCC4)=NN=C3C5=C(F)C=CC=C5FMolecular Formula :
C19H17F2N7OMolecular Weight :
397.38References & Citations :
[1]Atack JR, et al. MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans. J Psychopharmacol. 2011 Mar;25 (3) :314-28.Shipping Conditions :
Room temperatureScientific Category :
Reference StandardsCAS Number :
[233275-76-8]

