IR808-TZ

CAT: 0804-HY-155370Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-155370Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

IR808-TZ is a Tetraazine base station shipped with. IR808-TZ is a biocompatible PROTAC (BT-PROTAC) that can activate MZ1 and reduce BRD4 specificity[1].

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ir808-tz.html

Solubility

10 mM in DMSO

Smiles

CC1(C(/C=C/C(CCC/C2=C\C=C3N(C4=C(C\3(C)C)C=CC=C4)CCCCCC(NCC5=NN=C(N=N5)C)=O)=C2Cl)=[N+](C6=CC=CC=C61)CCCCCC(O)=O)C.F[P-](F)(F)(F)(F)F

Molecular Formula

C46H57ClF6N7O3P

Molecular Weight

936.41

References & Citations

[1]Tao Bi, et al. Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation. J Med Chem . 2023 Oct 23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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