IR808-TZ

• Description :

  IR808-TZ is a Tetraazine base station shipped with. IR808-TZ is a biocompatible PROTAC (BT-PROTAC) that can activate MZ1 and reduce BRD4 specificity[1].

• UNSPSC :

  12352005

• Target :

  PROTACs

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ir808-tz.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1(C(/C=C/C(CCC/C2=C\C=C3N(C4=C(C\3(C)C)C=CC=C4)CCCCCC(NCC5=NN=C(N=N5)C)=O)=C2Cl)=[N+](C6=CC=CC=C61)CCCCCC(O)=O)C.F[P-](F)(F)(F)(F)F

• Molecular Formula :

  C46H57ClF6N7O3P

• Molecular Weight :

  936.41

• References & Citations :

  [1]Tao Bi, et al. Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation. J Med Chem . 2023 Oct 23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported