PSB-12054

• Description :

  PSB-12054 is a selective P2X4 antagonist with an IC50 of 0.189 μM at human P2X4 receptors. PSB-12054 can be used in the research of neuropathic pain and neurodegenerative diseases[1].

• CAS Number :

  [1407632-07-8]

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  P2X Receptor

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(OCC=1C=CC=CC1)N2C=3C=CC=CC3OC=4C=CC=CC42

• Molecular Formula :

  C20H15NO3

• Molecular Weight :

  317.34

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

• References & Citations :

  [1]Hernandez-Olmos V, et al. N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem. 2012 Nov 26;55 (22) :9576-88.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  P2X4 Receptor