Products for Research Use Only
RegisterLogin

IMR-1A (Standard)

CAT: 0804-HY-100431AR-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-100431AR-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IMR-1A (Standard) is the analytical standard of IMR-1A. This product is intended for research and analytical applications. IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC50 of 0.5 μM. IMR-1A has a 50-fold increase in potency with respect to IMR-1. IMR-1 can metabolize in vivo to IMR-1A[1].
CAS Number
331862-41-0
UNSPSC
12352005
Target
Drug Metabolite; Notch; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(O)COC1=CC=C(/C=C(SC(N2)=S)\C2=O)C=C1OC
Molecular Formula
C13H11NO5S2
Molecular Weight
325.36
References & Citations
[1]Astudillo L et al. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res. 2016 Jun 15;76 (12) :3593-603.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-100431A-01IMR-1A
HY-100431-01IMR-1
HY-155383TNIR7-1A
HY-P3915-01Esculentin 1A
HY-136532-01ZT-1a
HY-N14785Deflectin 1a
HY-N14581Roselipin 1A
HY-163121PST3.1a
HY-134913Rhodblock 1a
HY-P5176Latartoxin-1a

Alternative Products

CatalogName
MBS2104031-01Rat Coronin 1A (CORO1A) Antibody Pair Kit (with Standard)
HK209971Coronin 1a (CORO1A) Human qPCR Template Standard (NM_007074)
HK203842HSP70-1A (HSPA1A) Human qPCR Template Standard (NM_005345)
PH310753Coronin 1a (CORO1A) (NM_007074) Human Mass Spec Standard
HK207131Syntaxin 1a (STX1A) Human qPCR Template Standard (NM_004603)
MBS2104030-01Human Coronin 1A (CORO1A) Antibody Pair Kit (with Standard)
MBS2103646-01Mouse Torsin 1A (TOR1A) Antibody Pair Kit (with Standard)
MBS2103645-01Human Torsin 1A (TOR1A) Antibody Pair Kit (with Standard)
MBS2101848-01Mouse Uroplakin 1A (UPK1A) Antibody Pair Kit (with Standard)
MBS2101847-01Human Uroplakin 1A (UPK1A) Antibody Pair Kit (with Standard)

Popular Products