Pomalidomide-PEG2-OH

• UNSPSC Description:

  Pomalidomide-PEG3-OH (compound 53a) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984)-based cereblon ligand and a 2-unit PEG linker[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pomalidomide-peg2-oh.html

• Smiles:

  O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCO)=CC=C3)=O)=O

• Molecular Weight:

  361.35

• References & Citations:

  [1]Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15;192:112186.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2143097-10-1