Pomalidomide-PEG2-OH

• Description :

  Pomalidomide-PEG3-OH (compound 53a) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984) -based cereblon ligand and a 2-unit PEG linker[1].

• UNSPSC :

  12352005

• Target :

  E3 Ligase Ligand-Linker Conjugates

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/pomalidomide-peg2-oh.html

• Smiles :

  O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCO)=CC=C3)=O)=O

• Molecular Formula :

  C17H19N3O6

• Molecular Weight :

  361.35

• References & Citations :

  [1]Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15;192:112186.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Cereblon

• CAS Number :

  [2143097-10-1]