HB-230

• Description :

  HB-230 is a red fluorescent transglutaminase 2 (TG2) probe. HB-230 complexes with TG2 and α2-macroglobulin via the LRP1 pathway for efficient endocytosis. The excitation and emission wavelengths of HB-230 are 649 and 665 nm, respectively[1].

• UNSPSC :

  12352005

• Target :

  Fluorescent Dye; Glutaminase

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Smiles :

  O=C(N1[C@@H](CCC1)C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)[C@@H](NC([C@H](CC/C=C/C(N(C)C)=O)NC([C@H]3N(CCC3)C(C)=O)=O)=O)CCNC(CCCCC[N+]4=C(/C=C/C=C/C=C5C(C)(C6=CC(S(=O)(O)=O)=CC=C6N\5C)C)C(C)(C)C7=CC(S(=O)([O-])=O)=CC=C47)=O

• Molecular Formula :

  C66H86N10O14S2

• Molecular Weight :

  1307.58

• References & Citations :

  [1]Chaitan Khosla, et al. Compositions and methods for transglutaminase-mediated endocytosis. WO2024049543A1. USA. 2024-03-07.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3031522-14-9]