Ginsenoside Rc

• Description:

  Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA) -mediated ion channel currents (IGABA) . Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.

• Product Name Alternative:

  Panaxoside Rc

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  GABA Receptor; Interleukin Related; TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Ginsenoside-Rc.html

• Purity:

  98.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

• Smiles:

  C[C@](CC/C=C(C)/C)([C@]1([H])[C@]([C@H](O)C[C@@]2([H])[C@@]3(C)CC[C@]4([H])[C@]2(C)CC[C@H](O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C4(C)C)([H])[C@@]3(C)CC1)O[C@@H]7O[C@H](CO[C@@H]8O[C@@H](CO)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O

• Molecular Formula:

  C53H90O22

• Molecular Weight:

  1079.27

• Precautions:

  H302

• References & Citations:

  [1]Lee BH, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36 (1) :55-60.|[2]Yu T, et al. Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-bindingkinase 1/interferon regulatory factor-3 and p38/ATF-2. J Ginseng Res. 2017 Apr;41 (2) :127-133.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  IL-1; TNFRSF5/CD40

• CAS Number:

  11021-14-0