Ginsenoside Rc

• Description :

  Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA) -mediated ion channel currents (IGABA) . Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.

• CAS Number :

  [11021-14-0]

• Product Name Alternative :

  Panaxoside Rc

• UNSPSC :

  12352005

• Hazard Statement :

  H302

• Target :

  GABA Receptor; Interleukin Related; TNF Receptor

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer; Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Ginsenoside-Rc.html

• Purity :

  98.0

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

• Smiles :

  C[C@](CC/C=C(C)/C)([C@]1([H])[C@]([C@H](O)C[C@@]2([H])[C@@]3(C)CC[C@]4([H])[C@]2(C)CC[C@H](O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C4(C)C)([H])[C@@]3(C)CC1)O[C@@H]7O[C@H](CO[C@@H]8O[C@@H](CO)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O

• Molecular Formula :

  C53H90O22

• Molecular Weight :

  1079.27

• Precautions :

  H302

• References & Citations :

  [1]Lee BH, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36 (1) :55-60.|[2]Yu T, et al. Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-bindingkinase 1/interferon regulatory factor-3 and p38/ATF-2. J Ginseng Res. 2017 Apr;41 (2) :127-133.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  IL-1; TNFRSF5/CD40