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(R, R) -VRT-534

CAT: 0931-TYD-03939-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TYD-03939-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
926664-33-7
Target
Gap Junction Protein
Related Pathways
Cytoskeletal Signaling
Bioactivity
(R, R) -VRT-534 is the (R, R) -enantiomer of VRT-534. VRT-534 (Compound 3) acts as a chemical chaperone targeting connexin 26 (Cx26) . VRT-534 demonstrates dose-dependent binding with recombinant WT Cx26 and mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. VRT-534 is applicable in research related to hearing impairments.
Smiles
C(NC=1SC([C@@H](C2=C(Cl)C=CC=C2)N3C[C@H](O)CC3)=CN1)(=O)C4(CC4)C=5C=C6C(=CC5)OCO6
Molecular Formula
C25H24ClN3O4S
Molecular Weight
497.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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