VRT-532

• Target :

  CFTR

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  >99.99%

• Bioactivity :

  VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Modification of CFTR by this small molecule modulator can increase arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag), thus reducing the accumulation of 4-chondroitin sulfate in cystic fibrosis.

• Smiles :

  CC1=CC=C(O)C(=C1)C1=NNC(=C1)C1=CC=CC=C1

• Molecular Formula :

  C16H14N2O

• Molecular Weight :

  250.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  38214-71-0