VRT-532

• Target:

  CFTR

• Related Pathways:

  Membrane transporter/Ion channel

• Purity:

  >99.99%

• Bioactivity:

  VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Modification of CFTR by this small molecule modulator can increase arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag), thus reducing the accumulation of 4-chondroitin sulfate in cystic fibrosis.

• Smiles:

  CC1=CC=C (O) C (=C1) C1=NNC (=C1) C1=CC=CC=C1

• Molecular Formula:

  C16H14N2O

• Molecular Weight:

  250.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  38214-71-0