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D-KLA Peptide

CAT: 0931-TP2656-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2656-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
286380-05-0
Target
Caspase, PARP, Mitochondrial Metabolism
Related Pathways
Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic, Proteases/Proteasome, Metabolism
Bioactivity
D-KLA Peptide, a synthetic pro-apoptotic peptide, selectively targets and induces apoptosis in mitochondria by disrupting the mitochondrial membrane. It activates apoptosis-related biochemical pathways, notably those involving caspase family proteins and PARP (poly ADP ribose polymerase) . Additionally, d-KLA Peptide facilitates the delivery of genes or small molecules, amplifying its anti-tumor properties.
Smiles
[C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@@H](CCCCN)N)=O)CC(C)C)=O)C)=O)CCCCN)=O)CC(C)C)=O)C)=O)CCCCN)=O)(C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CCCCN)C(O)=O)=O)C)=O)CC(C)C)=O)CCCCN)=O)C)=O)CC(C)C)=O)CCCCN
Molecular Formula
C72H138N20O15
Molecular Weight
1523.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C