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KLA peptide (acetate)

CAT: 0804-HY-P5345A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P5345A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KLA peptide acetate a cationic amphipathic mitochondrial membrane disrupting peptide that induces cell apoptosis by disrupting mitochondrial membrane. KLA peptide acetate can be used for the researches of cancer, inflammation, and neurological disease[1][2].
UNSPSC
12352209
Target
Apoptosis
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Purity
99.81
Solubility
H2O : ≥ 100 mg/mL
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.CC(O)=O.[x]
Molecular Formula
C72H138N20O15.xC2H4O2
Molecular Weight
1523.99 (free base)
References & Citations
[1]Guo Z, et al. Specific hepatic stellate cell-penetrating peptide targeted delivery of a KLA peptide reduces collagen accumulation by inducing apoptosis. J Drug Target. 2017 Sep;25 (8) :715-723.|[2]Zen R, et al. Pro-inflammatory microglia-targeted peptide therapy ameliorates neonatal hypoxic-ischemic encephalopathy in mice. Mol Ther. 2025 Jul 2;33 (7) :3177-3194.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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