BMS-986189

• Target:

  PD-1/PD-L1

• Related Pathways:

  Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis

• Bioactivity:

  BMS-986189, a macrocyclic peptide inhibitor of PD-L1 (IC 50: 1.03 nM), can be utilized for cancer research [1].

• Smiles:

  C (C=1C=2C (N (CC (O) =O) C1) =CC=CC2) [C@H]3C (=O) N (C) [C@@H] (CCCC) C (=O) N (C) [C@@H] (CCCC) C (=O) N[C@@H] (CC (C) C) C (=O) N[C@H] (C (NCC (N) =O) =O) CSCC (=O) N[C@@H] (CC4=CC=C (O) C=C4) C (=O) N (C) [C@@H] (C) C (=O) N[C@@H] (CC (N) =O) C (=O) N5[C@] (C (=O) N[C@@H] (CN) C (=O) N[C@@H] (CC (C) C) C (=O) N6[C@] (C (=O) N[C@@H] (CC=7C=8C (NC7) =CC=CC8) C (=O) N[C@@H] (CCN) C (=O) N3) (C[C@@H] (O) C6) [H]) (CCC5) [H]

• Molecular Formula:

  C91H131N21O21S

• Molecular Weight:

  1887.21

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1629665-96-8