BMS-986189

• Target :

  PD-1/PD-L1

• Related Pathways :

  Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis

• Bioactivity :

  BMS-986189, a macrocyclic peptide inhibitor of PD-L1 (IC 50: 1.03 nM), can be utilized for cancer research [1].

• Smiles :

  C(C=1C=2C(N(CC(O)=O)C1)=CC=CC2)[C@H]3C(=O)N(C)[C@@H](CCCC)C(=O)N(C)[C@@H](CCCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(NCC(N)=O)=O)CSCC(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(C)C)C(=O)N6[C@](C(=O)N[C@@H](CC=7C=8C(NC7)=CC=CC8)C(=O)N[C@@H](CCN)C(=O)N3)(C[C@@H](O)C6)[H])(CCC5)[H]

• Molecular Formula :

  C91H131N21O21S

• Molecular Weight :

  1887.21

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1629665-96-8