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BMS-986189

CAT: 0931-TP2550-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2550-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1629665-96-8
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis
Bioactivity
BMS-986189, a macrocyclic peptide inhibitor of PD-L1 (IC 50: 1.03 nM), can be utilized for cancer research [1].
Smiles
C(C=1C=2C(N(CC(O)=O)C1)=CC=CC2)[C@H]3C(=O)N(C)[C@@H](CCCC)C(=O)N(C)[C@@H](CCCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(NCC(N)=O)=O)CSCC(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(C)C)C(=O)N6[C@](C(=O)N[C@@H](CC=7C=8C(NC7)=CC=CC8)C(=O)N[C@@H](CCN)C(=O)N3)(C[C@@H](O)C6)[H])(CCC5)[H]
Molecular Formula
C91H131N21O21S
Molecular Weight
1887.21
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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