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Gallinamide A TFA

CAT: 0931-TN7689-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN7689-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1352920-57-0
Target
Cysteine Protease, Parasite, SARS-CoV
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
Gallinamide A TFA is a peptide that exhibits linear deposition and serves as a potent inhibitor of cathepsin L (CatL) with an IC50 of 17.6 pM. It inhibits SARS-CoV-2 infection by targeting CatL (EC50: 28 nM) and also inhibits Plasmodium falciparum with an IC50 of 50 nM [1] [2].
Smiles
C(C(O)=O)(F)(F)F.C(/C=C/[C@@H](NC([C@@H](NC([C@@H](OC([C@H]([C@H](CC)C)N(C)C)=O)CC(C)C)=O)CC(C)C)=O)C)(=O)N1[C@@H](C)C(OC)=CC1=O
Molecular Formula
C33H53F3N4O9
Molecular Weight
706.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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