Products for Research Use Only
RegisterLogin

Gallinamide A (TFA)

CAT: 0804-HY-N10109A-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N10109A-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM) . Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC50: 28 nM) . Gallinamide A TFA also inhibits Plasmodium falciparum (IC50: 50 nM) [1][2].
CAS Number
1352920-57-0
UNSPSC
12352005
Target
Cathepsin; Parasite; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gallinamide-a-tfa.html
Purity
99.85
Solubility
10 mM in DMSO
Smiles
CC[C@H](C)[C@H](N(C)C)C(O[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)/C=C/C(N1[C@H](C(OC)=CC1=O)C)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C33H53F3N4O9
Molecular Weight
706.79
References & Citations
[1]Ashhurst AS, et al. Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L. bioRxiv [Preprint]. 2020 Dec 24:2020.12.23.424111.|[2]Stoye A, et al. Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials. J Med Chem. 2019 Jun 13;62 (11) :5562-5578.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N10109-01Gallinamide A
HY-P5380ATNO211 (TFA)
HY-P4668A-01Valylleucine (TFA)
HY-P11296A-01LLVK (TFA)
HY-P10927A-01BRP (TFA)
HY-P10333A-01LIH383 (TFA)
HY-P3970D-01KQFK (TFA)
HY-P3460A-01TDSRCVIGLYHPPLQVY (TFA)
HY-P1723ASpexin (TFA)
HY-P10471A-01MPSD (TFA)

Alternative Products

CatalogName
TN7689-01Gallinamide A TFA
T72898-01Gallinamide A
A8967-1EZM0414 TFA
C8651-10Pentosidine TFA
A8958-100Box5 TFA
B5867-200SCH772984 TFA
B8792-5GsMTx4 TFA
330135Gardiquimod TFA
563453Cenupatide TFA
563651SSM3 TFA

Popular Products