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Lipid U 105

CAT: 0931-TCL-01230-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TCL-01230-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3049129-14-5
Target
Others
Related Pathways
Others
Bioactivity
Lipid U 105, an ionizable cationic lipid (pKa = 6.65), is employed in formulating lipid nanoparticles (LNPs) for delivering circular RNA both in vitro and in vivo. These LNPs, containing lipid U 105 and circular RNA for VEGF-A, enhance VEGF-A levels, boosting the proliferation and migration of human umbilical vein endothelial cells (HUVECs) . Moreover, applying these LNPs topically accelerates wound healing in diabetic mice on a high-fat and -sugar diet.
Smiles
O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCN(CCCN(CCO)CCO)CCCCCC(=O)OC(CCCCCCCC)CCCCCCCC
Molecular Formula
C53H106N2O6
Molecular Weight
867.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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