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HSD17B13-IN-105

CAT: 0931-T211179-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211179-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3012624-88-0
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-105 (Compound EX.87) is a selective inhibitor of 17β-hydroxysteroid dehydrogenase 13 (17BHSD13) with an IC50 value of 0.036 μM, demonstrating high selectivity over 17BHSD4, which has an IC50 value of 31.5 μM. HSD17B13-IN-105 shows potential for research in liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) .
Smiles
FC1=C(C2=NC(C(=O)N3C[C@@H](C)O[C@@H](C)C3)=NO2)C=C(F)C(F)=C1O
Molecular Formula
C15H14F3N3O4
Molecular Weight
357.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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