Products for Research Use Only

Inbrx-105

CAT: 0931-T9901A-783-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T9901A-783-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2539845-73-1
Target
PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint, Immunology/Inflammation, Apoptosis
Bioactivity
INBRX-105 is a recombinant humanized bispecific antibody that targets programmed death-ligand 1 (PD-L1) and 4-1BB (CD137), exhibiting potential checkpoint inhibition, immune stimulation, and anti-tumor activity. By binding to 4-1BB on activated T-lymphocytes and PD-L1 on tumor cells, INBRX-105 enhances T-cell co-stimulation and inhibits PD-L1-mediated T-cell suppression, potentially reducing tumor growth. It demonstrates anti-tumor efficacy and increased T-cell frequency in patients with solid tumors and in vivo. Molecular weight: 101.9 kD.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Popular Products