Fumagilin-105

• UNSPSC Description:

  Fumagilin-105 is an autophagy targeting chimera (AUTOTAC) that induces p62 self-oligomerization with DC50 values of 0.7 μM for MetAP2 in HEK293 cells[1].

• Target Antigen:

  Autophagy; AUTOTACs; Estrogen Receptor/ERR; p62

• Type:

  Reference compound

• Related Pathways:

  Autophagy;PROTAC;Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fumagilin-105.html

• Solubility:

  DMSO : 63 mg/mL (ultrasonic)

• Smiles:

  O=C(/C=C/C=C/C=C/C=C/C(OC1C(OC)C(C2(C)OC2C/C=C(C)\C)C3(OC3)CC1)=O)NCCOCCOCCNCC4=CC(OCC5=CC=CC=C5)=CC=C4

• Molecular Weight:

  784.98

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2410081-58-0