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SMARCA2 degrader-17

CAT: 0931-T89965-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89965-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2755761-78-3
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
SMARCA2 degrader-17 is a degrader of SMARCA2, exhibiting synergistic antiproliferative effects with Adagrasib in cancer cells and capable of inhibiting tumor growth.
Smiles
OC1=C(C=2C=C3N4[C@](CN(CC4)[C@H]5CN(C[C@@H](OC=6C=C([C@H](C(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C9=C(C)N=CS9)=O)C[C@@H](O)C7)[C@@H](C)C)ON6)C)CC5)(CNC3=NN2)[H])C=CC=C1
Molecular Formula
C47H58N10O6S
Molecular Weight
891.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C