PD-L1-IN-7

CAT: 0931-MF-0122636-01Size: 10 mgDry Ice: NoHazardous: No

CAT#:0931-MF-0122636-01Size:10 mg

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AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3024733-03-4

Target

PD-1/PD-L1

Related Pathways

Cell Cycle/Checkpoint|||Immunology/Inflammation|||Apoptosis

Bioactivity

PD-L1-IN-7 (compound CB31) serves as a PD-L1 inhibitor, effectuating PD-L1 internalization and retention within cells. It restrains the PD-1/PD-L1 interaction (IC 50: 0.2 nM), alters glycosylation patterns, and facilitates PD-L1 degradation. Additionally, PD-L1-IN-7 enhances T cell infiltration, boosts T cell function, and augments the capacity to destroy tumor cells.

Smiles

CC1=C(C2=C3C(N(N=C3)C4=CC(OC)=C(CN(C)[C@H]5[C@@H](O)COCC5)C(OC)=C4)=CC=C2)C=CC=C1C=6OC=7C(N6)=CC(CN(C)[C@@H]8CC[C@@H](C(O)=O)CC8)=CC7C#N

Molecular Formula

C46H50N6O7

Molecular Weight

798.93

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-163958	PD-L1-IN-7
RG-P022507-01	Pd-1/Pd-L1 Inhibitor Impurity 7
MBS344271-01	PD-L1
HY-157811	PD-1/PD-L1-IN-40
BUP23735-01	PD-1/PD-L1-IN-NP19
HY-173464	PD-1/PD-L1-IN-55
HY-155959-01	PD-1/PD-L1-IN-33
HY-145771	PD-1/PD-L1-IN-20
HY-145768	PD-1/PD-L1-IN-18
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PD-L1-IN-7

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