JP-2-249

• Bioactivity:

  JP-2-249, a molecular glue, serves as an effective degrader of SMARCA2. At concentrations ranging from 1-10 ?M, JP-2-249 reduces the protein levels of SMARCA2 in MV-4-11 cells.

• Smiles:

  NC1=C (C=C (N=N1) C2=C (O) C=CC=C2) N3CCN (C (/C=C/C (=O) C4=CC=C (OC) C=C4) =O) CC3

• Molecular Formula:

  C25H25N5O4

• Molecular Weight:

  459.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3036530-41-0