JP-2-249

• Bioactivity:

  JP-2-249, a molecular glue, serves as an effective degrader of SMARCA2. At concentrations ranging from 1-10 ?M, JP-2-249 reduces the protein levels of SMARCA2 in MV-4-11 cells.

• Smiles:

  NC1=C(C=C(N=N1)C2=C(O)C=CC=C2)N3CCN(C(/C=C/C(=O)C4=CC=C(OC)C=C4)=O)CC3

• Molecular Formula:

  C25H25N5O4

• Molecular Weight:

  459.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3036530-41-0