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HDHODH-IN-8

CAT: 0931-T64360-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T64360-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2757405-31-3
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM, exhibiting significant antiproliferative activity and excellent aqueous solubility, and holds potential for tumor disease research, particularly lymphoma.
Smiles
O([C@H](C(F)(F)F)C)C1=C(C(NC2=C(F)C=CC=C2F)=O)C=C(F)C(NC(C(=C(C)O)C#N)=O)=C1
Molecular Formula
C21H15F6N3O4
Molecular Weight
487.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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