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KS-58

CAT: 0931-TP2979-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2979-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2549046-46-8
Target
Ras
Related Pathways
MAPK|||GPCR/G Protein
Bioactivity
KS-58 is a derivative of KRpep-2d. It acts as an inhibitory peptide for K-Ras (G12D), selectively binding to K-Ras. KS-58 is capable of penetrating cells and interrupts the interaction between intracellular Ras and effector proteins. It inhibits the proliferation of tumor cells and exhibits antitumor activity.
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@]4(N(C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC5=CC=C(F)C=C5)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCCC)NC(=O)[C@@]6(CSCCCSC[C@@](NC3=O)(C(=O)NCCC(=O)N7[C@](C(=O)N[C@@H](CCCC)C(=O)N6)(CCC7)[H])[H])[H])CCC4)[H]
Molecular Formula
C64H89FN12O14S2
Molecular Weight
1333.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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