KS 501

CAT: 0804-HY-117232Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-117232Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KS 501 is a potent and selective calmodulin inhibitor. KS 501 inhibits the activation of calmodulin kinase I and II, but has less effect against cyclic adenosine 3’,5’-monophosphate (cyclic AMP) -sensitive kinase. KS 501 inhibits the enzyme through interfering with calmodulin activation rather than through a direct effect on the enzyme. KS 501 can be used for the study of leukemia[1].
CAS Number
[120634-86-8]
UNSPSC
12352005
Target
Calmodulin
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
O[C@@H]1[C@H](O)[C@@H](OC2=C(C(CCCCCCC)=CC(O)=C2)C(OC3=CC(CCCCCCC)=CC(O)=C3)=O)O[C@@]1([C@H](O)CO)[H]
Molecular Formula
C33H48O10
Molecular Weight
604.73
References & Citations
[1]Hait WN, et al. Effects of KS-501, KS-502 and their enantiomers on calmodulin-sensitive enzyme activity and cellular proliferation. Biochem Pharmacol. 1995 Jun 29;50 (1) :69-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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