25-Hydroxytachysterol3

CAT: 0931-T88081-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T88081-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

39932-44-0

Target

Liver X Receptor, Vitamin, Aryl Hydrocarbon Receptor, PPAR

Related Pathways

Metabolism, Immunology/Inflammation, DNA Damage/DNA Repair

Bioactivity

25-Hydroxytachysterol3 is a metabolite of Vitamin D3 that inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts while promoting the differentiation of keratinocytes and the expression of antioxidant-related genes. It activates receptors including the vitamin D receptor (VDR), aryl hydrocarbon receptor (AhR), liver X receptor α/β (LXRα/β), and peroxisome proliferator-activated receptor γ (PPARγ), and enhances the expression of CYP24A1.

Smiles

C[C@@]12[C@](C(/C=C/C3=C(C)CC[C@H](O)C3)=CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]

Molecular Formula

C27H44O2

Molecular Weight

400.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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25-Hydroxytachysterol3

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