Products for Research Use Only
RegisterLogin

Z-DEVD-R110

CAT: 0013-GTR19282411-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19282411-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Z-DEVD-R110 is a fluorogenic caspase-3/7 substrate used to detect apoptosis. Its design, featuring DEVD peptides conjugated to rhodamine 110, enables sensitive monitoring of caspase activity in both live-cell imaging and cell lysate assays for cancer and neurobiology research.
CAS Number
223538-61-2
Field of Research
Cell Biology, Protein Biochemistry
Molecular Weight
1515.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(Z-Asp-Glu-Val-Asp)2-Rhodamine 110
CAS Number223538-61-2
PubChem CID16181078
IUPAC Name(4S)-5-[[(2S)-1-[[(2S)-3-carboxy-1-[[6'-[[(2S)-3-carboxy-2-[[(2S)-2-[[(2S)-4-carboxy-2-[[(2S)-3-carboxy-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-3-carboxy-2-(phenylmethoxycarbonylamino)propanoyl]amino]-5-oxopentanoic acid
Molecular FormulaC72H78N10O27
Molecular Weight1515.4
XLogP1.7
Topological Polar Surface Area569
Hydrogen Bond Donor Count16
Hydrogen Bond Acceptor Count27
Rotatable Bond Count40
Heavy Atom Count109
Formal Charge0
Complexity3130
SMILES
CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)NC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)OCC5=CC=CC=C5)C6=CC=CC=C6C(=O)O3)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)OCC7=CC=CC=C7
InChI
InChI=1S/C72H78N10O27/c1-35(2)59(81-61(95)45(23-25-53(83)84)75-65(99)49(31-57(91)92)79-70(104)106-33-37-13-7-5-8-14-37)67(101)77-47(29-55(87)88)63(97)73-39-19-21-43-51(27-39)108-52-28-40(20-22-44(52)72(43)42-18-12-11-17-41(42)69(103)109-72)74-64(98)48(30-56(89)90)78-68(102)60(36(3)4)82-62(96)46(24-26-54(85)86)76-66(100)50(32-58(93)94)80-71(105)107-34-38-15-9-6-10-16-38/h5-22,27-28,35-36,45-50,59-60H,23-26,29-34H2,1-4H3,(H,73,97)(H,74,98)(H,75,99)(H,76,100)(H,77,101)(H,78,102)(H,79,104)(H,80,105)(H,81,95)(H,82,96)(H,83,84)(H,85,86)(H,87,88)(H,89,90)(H,91,92)(H,93,94)/t45-,46-,47-,48-,49-,50-,59-,60-/m0/s1
InChIKey
MRLMIVOGDRELQK-DLODMIPSSA-N
Chemical Structure
2D Structure
2D structure of (Z-Asp-Glu-Val-Asp)2-Rhodamine 110
CAS: 223538-61-2
CID: 16181078
Formula: C72H78N10O27
MW: 1515.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1515.4
XLogP31.7
Hydrogen Bond Donor Count16
Hydrogen Bond Acceptor Count27
Rotatable Bond Count40
Exact Mass1514.50378725
Monoisotopic Mass1514.50378725
Topological Polar Surface Area569 Ų
Heavy Atom Count109
Formal Charge0
Complexity3130
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19282180-01Z-IETD-R110
GTR19162799-01Z-DEVD-FMK
GTR19035123Z-DEVD-CMK
GTR19067335-01Z-DEVD-FMK
GTR18919175Z-DEVD-FMK
GTR18894433Z-DEVD-FMK
GTR19282414Z-DEVD-AFC
GTR19266964-01Z-AA-R110-PEG
GTR19282413-01Z-DEVD-AMC
GTR18897961-01Z-DEVD-AMC peptide

Alternative Products

CatalogName
T87662-01Z-DEVD-R110
13430-AAT(Z-DEVD) 2-R110
#10226Ac-DEVD-R110, 1 mg
T208187-01Z-IETD-R110
10209Z-FR-R110 5mg
TXB-00784-01Z-AA-R110-PEG
561669Z-DEVD-fmk
HY-P3363-01Z-DEVD-AMC
ALX-260-048-M001Z-DEVD-pNA
sc-296746Z-DEVD-AFC

Popular Products