TH-Z816

• Target:

  Ras|||Kras

• Related Pathways:

  MAPK|||GPCR/G Protein

• Bioactivity:

  TH-Z816 acts as a reversible inhibitor targeting the KRAS (G12D) mutation, exhibiting an IC50 of 14 µM. This compound is utilized in cancer research [1].

• Smiles:

  C[C@H]1N(C2=C3C(CN(CC3)C=4C5=C(C=CC4)C=CC=C5C)=NC(OC[C@H]6N(C)CCC6)=N2)CCNC1

• Molecular Formula:

  C29H38N6O

• Molecular Weight:

  486.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2847881-42-7