TH-6

• Target:

  Others|||Apoptosis|||Reactive Oxygen Species|||HDAC

• Related Pathways:

  Apoptosis|||Immunology/Inflammation|||Chromatin/Epigenetic|||Others|||NF-?B|||DNA Damage/DNA Repair|||Metabolism

• Bioactivity:

  TH-6 is a potent inhibitor of HDAC, acting on HDAC1 (IC50: 0.115 ?M), HDAC2 (IC50: 0.135 ?M), HDAC3 (IC50: 0.242 ?M), HDAC6 (IC50: 0.138 ?M), HDAC8 (IC50: 2.120 ?M) . TH-6 inhibits cell migration and invasion and exhibits anti-tumour effects.

• Molecular Formula:

  C22H24FN3O5

• Molecular Weight:

  429.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C