MK-8457

• Target:

  Syk

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].

• Smiles:

  O[C@]1 (CC (C) (C) [C@@H] (C (O) =O) CC1) C=2SC (=CN2) C3=CC (NC=4N=C (C (F) (F) F) C=CN4) =CC (C) =C3

• Molecular Formula:

  C24H25F3N4O3S

• Molecular Weight:

  506.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1312518-84-5