PD-168077

CAT: 0804-HY-21098Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-21098Size:1 Each
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AVAILABILITY: InStock
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Description
PD-168077 is a selective dopamine D4 receptor agonist, with a Ki of 9 nM[1].
CAS Number
[190383-31-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pd-168077.html
Smiles
O=C(NCN1CCN(C2=CC=CC=C2C#N)CC1)C3=CC=CC(C)=C3
Molecular Formula
C20H22N4O
Molecular Weight
334.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Clifford JJ, et al. Topographically based search for an "Ethogram" among a series of novel D (4) dopamine receptor agonists and antagonists. Neuropsychopharmacology. 2000 May;22 (5) :538-44.|[2]Gu Z, et al. Activation of dopamine D4 receptors induces synaptic translocation of Ca2+/calmodulin-dependent protein kinase II in cultured prefrontal cortical neurons. Mol Pharmacol. 2006 Mar;69 (3) :813-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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