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INY-05-040

CAT: 0931-T86725-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86725-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2503018-29-7
Target
PROTACs, Akt
Related Pathways
PI3K/Akt/mTOR signaling, PROTAC, Cytoskeletal Signaling
Bioactivity
INY-05-040 is an AKT degrader that selectively and rapidly degrades all three AKT isoforms, inhibiting downstream signaling and cell proliferation in 288 cancer cell lines, exhibiting anti-cancer activity [1].
Smiles
C[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CNCCCCCCCCCCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)C(C)(C)C)=O)C7=CC=C(Cl)C=C7)=O)CC3
Molecular Formula
C55H76ClN9O6S
Molecular Weight
1026.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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