HSD17B13-IN-71

• Target :

  Dehydrogenase

• Related Pathways :

  Metabolism

• Bioactivity :

  HSD17B13-IN-71 (Compound 149), an effective inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), displays potent activity with an IC 50 value of ? 0.1 ?M against estradiol. This compound is applicable in the study of various disorders including liver diseases, metabolic diseases, and cardiovascular conditions such as NAFLD or NASH, in addition to drug-induced liver injury (DILI) [1].

• Smiles :

  N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C(F)F)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

• Molecular Formula :

  C25H16Cl2F5N3O4

• Molecular Weight :

  588.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2770247-40-8