HC-5404

• Target :

  PERK

• Related Pathways :

  Apoptosis

• Purity :

  0.9933

• Bioactivity :

  HC-5404 is a novel, potent and highly selective PERK (Protein kinase RNA-like Endoplasmic Reticulum Kinase) inhibitor, blocking the activation of the PERK pathway, which in turn inhibits the endoplasmic reticulum stress response signaling pathway, thereby exerting anti-tumor effects, and can be used to treat advanced solid tumors and renal cell Cancer.

• Smiles :

  CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1

• Molecular Formula :

  C24H24F2N4O3

• Molecular Weight :

  454.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2247396-91-2