HC-258

• Target:

  YAP

• Related Pathways:

  Stem Cells

• Bioactivity:

  HC-258 is a direct TEAD inhibitor that forms a covalent bond with Cys380, a cysteine residue of TEAD proteins, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 in MDA-MB-231 cells.

• Smiles:

  O=C (C=C) NC1=CC=CC (=C1) NC=2C=CC=C (OCCCCC) C2

• Molecular Formula:

  C20H24N2O2

• Molecular Weight:

  324.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3056128-12-9