HC-258

• Target :

  YAP

• Related Pathways :

  Stem Cells

• Bioactivity :

  HC-258 is a direct TEAD inhibitor that forms a covalent bond with Cys380, a cysteine residue of TEAD proteins, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 in MDA-MB-231 cells.

• Smiles :

  O=C(C=C)NC1=CC=CC(=C1)NC=2C=CC=C(OCCCCC)C2

• Molecular Formula :

  C20H24N2O2

• Molecular Weight :

  324.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3056128-12-9