DC-SX029

• Target:

  PI3K|||I?B/IKK|||NF-?B

• Related Pathways:

  PI3K/Akt/mTOR signaling|||NF-?B

• Bioactivity:

  DC-SX029 is a potent inhibitor of SNX10 protein-protein interaction (PPI) with an estimated K D constant of approximately 0.935 ?M as measured by surface plasmon resonance (SPR) . It blocks the SNX10-PIKfyve interaction, leading to decreased TBK1/c-Rel signaling activation, without affecting SNX10 protein levels. DC-SX029 shows potential for inflammatory bowel disease (IBD) research [1].

• Smiles:

  S (NCC (CCC (O) =O) C (F) (F) F) (=O) (=O) C1=CC=C (NC (OC) =O) C=C1

• Molecular Formula:

  C14H17F3N2O6S

• Molecular Weight:

  398.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  300713-88-6