DC-SX029

• Target :

  PI3K|||I?B/IKK|||NF-?B

• Related Pathways :

  PI3K/Akt/mTOR signaling|||NF-?B

• Bioactivity :

  DC-SX029 is a potent inhibitor of SNX10 protein-protein interaction (PPI) with an estimated K D constant of approximately 0.935 ?M as measured by surface plasmon resonance (SPR) . It blocks the SNX10-PIKfyve interaction, leading to decreased TBK1/c-Rel signaling activation, without affecting SNX10 protein levels. DC-SX029 shows potential for inflammatory bowel disease (IBD) research [1].

• Smiles :

  S(NCC(CCC(O)=O)C(F)(F)F)(=O)(=O)C1=CC=C(NC(OC)=O)C=C1

• Molecular Formula :

  C14H17F3N2O6S

• Molecular Weight :

  398.36

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  300713-88-6