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DC 432

CAT: 0931-T83949Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T83949Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2388988-70-1
Target
Others
Related Pathways
Others
Bioactivity
DC 432, a potent peptidomimetic inhibitor of N-terminal methyltransferase 1/2 (NTMT1/2) with an IC50 value of 54 nM, incorporates a BM30 peptide enhanced by five arginine residues. It effectively reduces the N-terminal methylation level of the regulator of chromosome condensation 1 and SET proteins in HCT116 cells, demonstrating cell permeability.
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)[C@@H]1N(C(CC2=CC=C(O)C=C2)=O)CCC1
Molecular Formula
C55H100N28O10
Molecular Weight
1313.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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