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CSF1R-IN-15

CAT: 0931-T86098-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86098-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2925744-43-8
Target
C-Fms
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
CSF1R-IN-15 (compound 23) serves as an inhibitor of the colony-stimulating factor-1 receptor (CSF1R), a tyrosine kinase located in the macrophage cell membrane. This receptor is activated by colony-stimulating factor-1 (CSF-1) and interleukin-34. Signaling through CSF1R is essential for the differentiation, proliferation, and survival of macrophages [1].
Smiles
N(CC1=CC(C)=CC=C1)(C)C2=C3C(NC(=C3)C4=CC=C(CO)C=C4)=NC=N2
Molecular Formula
C22H22N4O
Molecular Weight
358.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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