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Anticancer agent 109

CAT: 0931-T85667-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T85667-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2097497-16-8
Target
TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Anticancer agent 109 (compound 6-15) acts as an inhibitor targeting the Gas6-Axl axis, demonstrating significant anti-cancer properties. This compound suppresses the expression of Gas6, Axl, p-PI3K, and p-AKT in cancer cells, thereby inducing G1 phase arrest and promoting apoptosis of cancer cells. Additionally, Anticancer agent 109 effectively inhibits tumor growth in nude mouse tumor-bearing models [1].
Smiles
C(=C\1/C=2C(NC1=O)=NC(C)=C(O)C2C)\C3=NC4=C(C=C3)C=CC=C4
Molecular Formula
C19H15N3O2
Molecular Weight
317.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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