(Rac) -SAG

• Target:

  Smo

• Related Pathways:

  Stem Cells

• Bioactivity:

  (Rac) -SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC?? = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamine's inhibition of Smo [1] [2] [3].

• Smiles:

  N(C(=O)C1=C(Cl)C=2C(S1)=CC=CC2)(CC3=CC(=CC=C3)C=4C=CN=CC4)C5CCC(NC)CC5

• Molecular Formula:

  C28H28ClN3OS

• Molecular Weight:

  490.06

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  364590-63-6