SAG

• Target:

  Hedgehog/Smoothened|||Smo

• Related Pathways:

  Stem Cells|||GPCR/G Protein

• Purity:

  0.9888

• Bioactivity:

  SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.

• Smiles:

  CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl

• Molecular Formula:

  C28H28ClN3OS

• Molecular Weight:

  490.06

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  912545-86-9