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SAG dihydrochloride

CAT: 0931-T40465-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T40465-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2702366-44-5
Target
Smo, Hedgehog/Smoothened
Related Pathways
Stem Cells, GPCR/G Protein
Purity
>99.99%
Bioactivity
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.
Smiles
O=C(C1=C(C2=CC=CC=C2S1)Cl)N([C@@H]3CC[C@H](CC3)NC)CC4=CC(C5=CC=NC=C5)=CC=C4.Cl.Cl
Molecular Formula
C28H30Cl3N3OS
Molecular Weight
562.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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