PH-HG-005-5

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  PH-HG-005-5 (compound 16c), a SN-38 derivative, serves as a Drug-Linker Conjugate for Antibody-Drug Conjugates (ADCs) manufacture. It possesses the capability to conjugate with targeting peptides for ADC synthesis [1].

• Smiles:

  O(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@]2(CC)C3=C(C(=O)N4C(=C3)C=5C(C4)=C(CC)C=6C(N5)=CC=C(O)C6)COC2=O

• Molecular Formula:

  C41H47N7O10

• Molecular Weight:

  797.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2810895-93-1