RB-005

• Target :

  S1P Receptor|||Others

• Related Pathways :

  GPCR/G Protein|||Others

• Bioactivity :

  RB-005 is a potent sphingosine kinase isoform 1 (SK1) inhibitor, which may serve as therapeutic agent for proliferative diseases, including hypertension. RB-005, (IC (50) = 3.6 ?M), which also induced proteasomal degradation of SK1 in human pulmonary arterial smooth muscle cells.

• Smiles :

  C(CN1CCC(O)CC1)C2=CC=C(CCCCCCCC)C=C2

• Molecular Formula :

  C21H35NO

• Molecular Weight :

  317.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1425049-20-2