HZ-A-005

• Target:

  Others|||BTK

• Related Pathways:

  Others|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  HZ-A-005 is a selective, potent, covalent inhibitor of Bruton's tyrosine kinase (BTK) . HZ-A-005 significantly inhibits tumour growth in a xenograft mouse model.

• Smiles:

  NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)[C@@H]5CN(C(C(=C)Cl)=O)CCC5)=NC=N1

• Molecular Formula:

  C25H23ClN6O2

• Molecular Weight:

  474.94

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2041789-14-2