HG-12-6

CAT: 0931-T11559-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T11559-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2222354-57-4

Target

Others, IRAK

Related Pathways

Immunology/Inflammation, NF-κB, Others

Bioactivity

HG-12-6 is a type II inhibitor of IRAK4, demonstrating preferential binding to unphosphorylated inactive IRAK4 (IC50: 165 nM) and modulating IRAK4 activity in autoimmunity and inflammation.

Smiles

N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(N3)C4=CC(C(NC5=CC(C(F)(F)F)=C(CN6CCNCC6)C=C5)=O)=CC=C4

Molecular Formula

C29H27F3N6O2S

Molecular Weight

580.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5766806	HG-12-6
GTR19239034-01	HG-6-63-01
AT013	Mercury(Hg)
2013720/D	Mercury Hg
AG013	Chelant-Hg
GX4457-1l	Nickelbad 218 HG / Nickel bath 218 HG
RDM-FA-02	Fungal Agar —HG
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RDM-NB-02	Nutrient Broth HG
RDM-FB-02	Fungal Broth —HG

HG-12-6

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