KH-4-43

CAT: 0931-T84685-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T84685-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2813310-07-3

Target

E1/E2/E3 Enzyme, Others

Related Pathways

Others, Ubiquitination

Bioactivity

KH-4-43, an inhibitor of the E3 CRL4 ligase complex, demonstrates anticancer activity by targeting the core of the E3 CRL4. It exhibits a binding affinity (Kd) of 83 nM to the E3 ROC1-CUL4A CTD and 9.4 μM to the closely related ROC1-CUL1 CTD [1].

Smiles

C(F)(F)(F)C1=C(C(=O)C=2C(O1)=C(O)C(O)=CC2)C3=CN(N=C3)C4=CC=C(Cl)C=C4

Molecular Formula

C19H10ClF3N2O4

Molecular Weight

422.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T62398-01	KH-3
T15657-01	KH-CB19
T210097-01	HDAC6-IN-43
T209490-01	HPK1-IN-43
T208265-01	α-Glucosidase-IN-43
T8478-01	SC-43

Alternative Products

Catalog	Name
HY-148602-01	KH-4-43
sc-101375	CKR-4 (KH-4F5)
sc-101375 HRP	CKR-4 (KH-4F5) HRP
sc-101375 PE	CKR-4 (KH-4F5) PE
sc-101375 AC	CKR-4 (KH-4F5) AC
sc-101375 FITC	CKR-4 (KH-4F5) FITC
B7510-50	KH 7
BA4888-10	KH-3
BA3839-1	KH-CB20
HY-150503	KH-259

KH-4-43

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