KH-176M

CAT: 0931-T202419-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T202419-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2095304-61-1

Bioactivity

KH176m serves as a selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), effectively suppressing mPGES-1 expression. It inhibits the growth of DU145-derived spheroids, but does not affect cells with low mPGES-1 expression such as LNCaP. As an antioxidant and redox modulator, KH176m demonstrates high efficacy in combating cardiac oxidative stress, with its impact varying according to the duration of ischemia. It holds potential therapeutic value in alleviating acute cardiac ischemia-reperfusion injury (IRI) .

Smiles

C(C[C@](C(N[C@@H]1CCCNC1)=O)(C)O)C2=C(C)C(=O)C(C)=C(C)C2=O

Molecular Formula

C19H28N2O4

Molecular Weight

348.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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KH-176M

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