SC-43

• Target:

  Apoptosis|||Phosphatase|||STAT

• Related Pathways:

  JAK/STAT signaling|||Stem Cells|||Metabolism|||Apoptosis

• Purity:

  0.9926

• Bioactivity:

  SC-43 is a potent and orally active agonist of SHP-1 (PTPN6) . SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.

• Smiles:

  FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc(cc3)C#N)c2)ccc1Cl

• Molecular Formula:

  C21H13ClF3N3O2

• Molecular Weight:

  431.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1400989-25-4