ROCK-IN-10

CAT: 0931-MF-0119895-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0119895-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1038549-25-5
Target
Others|||ROCK
Related Pathways
Stem Cells|||Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Others
Bioactivity
ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].
Smiles
NC(=O)c1ccc(NC(=O)NCc2cccc(c2)C(=O)Nc2ccc3CCNCc3c2)cc1
Molecular Formula
C25H25N5O3
Molecular Weight
443.507
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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